Cardiomegaly and heart failure in a patient with prolactin-secreting pituitary tumour.

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Cardiomegaly and heart failure in a patient with prolactin-secreting pituitary tumour.

Unexplained cardiomegaly with cardiac failure was observed in a 42-year-old woman in whom a pituitary tumour had been treated by radiotherapy five years previously. She had been amenorrhoeic for 10 years. Thyroid and adrenal function was normal. Despite treatment with digitalis and diuretic, her cardiac disease progressed until she died suddenly at the age of 45. Hyperprolactinaemia was evident...

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Prolactin secreting pituitary carcinoma.

A man with a prolactin secreting pituitary carcinoma was treated by surgery and radiotherapy. Persistent hyperprolactinaemia partially responded to oral bromocriptine for four years. Serum prolactin then rose considerably with rapid, invasive tumour recurrence. Cytotoxic chemotherapy halted tumour progression for twelve months before fatal spread throughout the brain. Failure to normalise serum...

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Prolactin Secreting Pituitary Adenomas

Correspondence to: Ioana Muntean, e-mail: [email protected] ABSTRACT. Hyperprolactinemia has different etiologic forms, among them, the prolactin-secreting pituitary tumors represent an important entity. In our study, were analyzed the clinical aspects, diagnostic procedures and therapeutical approach of 31 cases of prolactinomas (F/M ratio = 27/4) hospitalized in the Clinic of Endocrinol...

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Synchronous GH- and prolactin-secreting pituitary adenomas

UNLABELLED Pituitary adenomas are usually solitary lesions. Rarely, patients may present with two distinct pituitary tumors. We report a case of synchronous secretory pituitary adenomas in a woman who initially presented with elevated prolactin levels. She was initially treated with cabergoline, but, after many years, she began developing symptoms consistent with acromegaly. Imaging revealed tw...

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Hormonal control of pituitary prolactin-secreting tumors.

Prolactin secreting adenomas (prolactinomas) are the most prevalent form of pituitary tumors in humans. Prolactinomas have been linked to estrogen exposure in humans and animals. However, the mechanism by which estrogen increases mitogenesis in lactotropes, as well as other estrogen responsive cells, is not well understood. Given the complex nature of steroid hormones and their wide array of ac...

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ژورنال

عنوان ژورنال: Thorax

سال: 1979

ISSN: 0040-6376

DOI: 10.1136/thx.34.3.328